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A 2023 meta-analysis examined probiotic effects on metabolic outcomes across 45 randomized controlled trials

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Similarly, patients with bleeding disorders or those at high risk for bleeding complications may require careful evaluation before initiating peptide therapy

This pattern holds biological significance in PD in that it suggests that disease- or treatment-related effects may exert selective pressure on the microbial network in the gut without necessarily lowering the overall number of microbial species present, thereby exerting an influence on GBA signaling and L-DOPA metabolism

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